![Mitogen‐activated protein kinase signaling mediates opioid‐induced presynaptic NMDA receptor activation and analgesic tolerance - Deng - 2019 - Journal of Neurochemistry - Wiley Online Library Mitogen‐activated protein kinase signaling mediates opioid‐induced presynaptic NMDA receptor activation and analgesic tolerance - Deng - 2019 - Journal of Neurochemistry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/ce01731e-a4ab-41c8-a8ea-907c5b7b67fe/jnc14628-fig-0008-m.png)
Mitogen‐activated protein kinase signaling mediates opioid‐induced presynaptic NMDA receptor activation and analgesic tolerance - Deng - 2019 - Journal of Neurochemistry - Wiley Online Library
![Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion | Semantic Scholar Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/4d3293c2088da60abdac11b52d2ea3b4ecc4f433/11-Figure2-1.png)
Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion | Semantic Scholar
![Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapses following acute stress | eLife Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapses following acute stress | eLife](https://iiif.elifesciences.org/lax/23785%2Felife-23785-fig7-v1.tif/full/,1500/0/default.jpg)
Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapses following acute stress | eLife
![Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons | Journal of Neuroscience Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons | Journal of Neuroscience](https://www.jneurosci.org/content/jneuro/35/37/12917/F3.large.jpg)
Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons | Journal of Neuroscience
![Kappa opioid receptor activation alleviates experimental autoimmune encephalomyelitis and promotes oligodendrocyte-mediated remyelination | Nature Communications Kappa opioid receptor activation alleviates experimental autoimmune encephalomyelitis and promotes oligodendrocyte-mediated remyelination | Nature Communications](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fncomms11120/MediaObjects/41467_2016_Article_BFncomms11120_Fig1_HTML.jpg)
Kappa opioid receptor activation alleviates experimental autoimmune encephalomyelitis and promotes oligodendrocyte-mediated remyelination | Nature Communications
Kappa opioid receptor (KOR) modulation of dopamine in the cortex and... | Download Scientific Diagram
![Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink](https://media.springernature.com/lw685/springer-static/image/chp%3A10.1007%2F164_2020_431/MediaObjects/500126_1_En_431_Fig1_HTML.png)
Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink
![Nalfurafine is a G-protein biased agonist having significantly greater bias at the human than rodent form of the kappa opioid receptor - ScienceDirect Nalfurafine is a G-protein biased agonist having significantly greater bias at the human than rodent form of the kappa opioid receptor - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0898656817300165-fx1.jpg)
Nalfurafine is a G-protein biased agonist having significantly greater bias at the human than rodent form of the kappa opioid receptor - ScienceDirect
![Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling](https://www.science.org/cms/10.1126/scisignal.aai8441/asset/236282b7-67c8-485b-87f5-2c5e8c53b95c/assets/graphic/9_ra117_f1.jpeg)
Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling
Peripheral Sensitization Increases Opioid Receptor Expression and Activation by Crotalphine in Rats | PLOS ONE
![Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12964-022-00833-3/MediaObjects/12964_2022_833_Figa_HTML.png)
Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text
![Opioids As Modulators of Cell Death and Survival—Unraveling Mechanisms and Revealing New Indications | Pharmacological Reviews Opioids As Modulators of Cell Death and Survival—Unraveling Mechanisms and Revealing New Indications | Pharmacological Reviews](https://pharmrev.aspetjournals.org/content/pharmrev/56/3/351/F1.large.jpg)
Opioids As Modulators of Cell Death and Survival—Unraveling Mechanisms and Revealing New Indications | Pharmacological Reviews
![Figure 5. | Stress-Induced p38 Mitogen-Activated Protein Kinase Activation Mediates κ-Opioid-Dependent Dysphoria | Journal of Neuroscience Figure 5. | Stress-Induced p38 Mitogen-Activated Protein Kinase Activation Mediates κ-Opioid-Dependent Dysphoria | Journal of Neuroscience](https://www.jneurosci.org/content/27/43/11614/F5.large.jpg)
Figure 5. | Stress-Induced p38 Mitogen-Activated Protein Kinase Activation Mediates κ-Opioid-Dependent Dysphoria | Journal of Neuroscience
![Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons | Journal of Neuroscience Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons | Journal of Neuroscience](https://www.jneurosci.org/content/jneuro/35/37/12917/F1.large.jpg)