Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender - ScienceDirect
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
A Small-Molecule Inhibitor of Human DNA Polymerase η Potentiates the Effects of Cisplatin in Tumor Cells | Biochemistry
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
IJMS | Free Full-Text | Detours to Replication: Functions of Specialized DNA Polymerases during Oncogene-induced Replication Stress | HTML
DNA polymerase κ: Friend or foe? | Science Signaling
DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide - ScienceDirect
Science Signaling - The DNA polymerase Pol-kappa endows tumor cells with resistance to the BRAF inhibitor vemurafenib without increasing mutagenesis, according to new research from the White lab. https://fcld.ly/5jaum2s Credit: K. Temprine
Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance | Science Signaling
DNA Polymerase Kappa Research Products: Novus Biologicals
Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? | PLOS Genetics
NF-κB inhibitors in treatment and prevention of lung cancer - ScienceDirect
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms
DNA polymerases and cancer | Nature Reviews Cancer
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? | PLOS Genetics
Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites | PNAS
RCSB PDB - 6BS1: Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion
DNA polymerase η promotes nonhomologous end joining upon etoposide exposure dependent on the scaffolding protein Kap1 - Journal of Biological Chemistry
Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis